Simple microdilution test for detection of metallo-beta-lactamase production in Pseudomonas aeruginosa.

نویسندگان

  • Roberta Migliavacca
  • Jean-Denis Docquier
  • Claudia Mugnaioli
  • Gianfranco Amicosante
  • Rossana Daturi
  • Kyungwon Lee
  • Gian Maria Rossolini
  • Laura Pagani
چکیده

A microdilution test measuring imipenem MICs in the presence or absence of a mixture of EDTA plus 1,10-phenanthroline was developed and tested on 190 Pseudomonas aeruginosa isolates, including 18 VIM- and 4 IMP-type metallo-beta-lactamase (MBL) producers. The chelator mixture reduced by fourfold or more the imipenem MICs for MBL producers, while a lower effect or no effect was usually observed with MBL nonproducers.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 40 11  شماره 

صفحات  -

تاریخ انتشار 2002